Terlipressin or norepinephrine, or both in septic shock?
نویسندگان
چکیده
منابع مشابه
Arginine vasopressin in septic shock: supplement or substitute for norepinephrine?
In the current issue of Critical Care, Simon and coworkers investigated the effects of first-line arginine vasopressin (AVP) on organ function and systemic metabolism compared with norepinephrine in a pig model of fecal peritonitis. AVP was titrated according to the mean arterial pressure suggesting a vasopressor rather than a hormone replacement therapy. The study provides some evidence for th...
متن کاملNorepinephrine or dopamine for the treatment of hyperdynamic septic shock?
STUDY OBJECTIVE To compare the ability of dopamine and norepinephrine to reverse hemodynamic and metabolic abnormalities of human hyperdynamic septic shock. DESIGN Prospective, double-blind, randomized trial. SETTING An ICU in a university hospital. PATIENTS Adult patients with hyperdynamic septic shock after fluid resuscitation. INTERVENTIONS Patients were assigned to receive either do...
متن کاملVasopressin and its analog terlipressin versus norepinephrine in the treatment of septic shock: a meta-analysis
Purpose: To compare the effectiveness and safety of vasopressin and its analog terlipressin with norepinephrine treatment in adult patients with septic shock and to explore the most effective and safe protocol. Materials and Methods: This study was based on Cochrane methodology for conducting meta-analysis. Only randomized controlled trials were eligible for this study. The participants were ad...
متن کاملCardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine
INTRODUCTION Cardiac troponins are sensitive and specific biomarkers of myocardial necrosis. We evaluated troponin, CK, and ECG abnormalities in patients with septic shock and compared the effect of vasopressin (VP) versus norepinephrine (NE) on troponin, CK, and ECGs. METHODS This was a prospective substudy of a randomized trial. Adults with septic shock randomly received, blinded, a low-dos...
متن کاملErratum to: Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine
Author details Department of Medicine and Interdepartmental Division of Critical Care Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada. University Health Network-General Division, University of Toronto, Toronto, Ontario, Canada. Intensive Care, Charing Cross Hospital, Imperial, College, London, UK. Departments of Medicine, Clinical Epidemiology & Biostatistics, Mc...
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ژورنال
عنوان ژورنال: Intensive Care Medicine
سال: 2018
ISSN: 0342-4642,1432-1238
DOI: 10.1007/s00134-018-5290-x